Sedentary Behaviour
What we do?
Our group has been at the forefront internationally in furthering the understanding of the relationship between sedentary behaviour and health. Our research in this area spans the whole translational research pathway from laboratory studies examining the impact of breaking up sitting time with different physical activity types on health, epidemiology work to understand the role of sedentary behaviour in morbidity and mortality, developing and testing the effectiveness and cost-effectiveness of sitting reduction interventions in different populations and contexts and then finally upscaling these interventions for implementation in real world settings.
Members
Highlighted Research
Pinto AJ, Bergouignan A, Dempsey PC, Roschel H, Owen N, Gualano B, Dunstan DW. Physiology of sedentary behavior. Physiol Rev. 2023 Oct 1;103(4):2561-2622. doi: 10.1152/physrev.00022.2022
Edwardson CL, Biddle SJH, Clemes SA, Davies MJ, Dunstan DW, Eborall H, Granat MH, Gray LJ, Healy GN, Jaicim NB, Lawton S, Maylor BD, Munir F, Richardson G, Yates T, Clarke-Cornwell AM. Effectiveness of an intervention for reducing sitting time and improving health in office workers: three arm cluster randomised controlled trial. BMJ. 2022 Aug 17;378:e069288. doi: 10.1136/bmj-2021-069288
Dempsey PC, Strain T, Winkler EAH, Westgate K, Rennie KL, Wareham NJ, Brage S, Wijndaele K. Association of Accelerometer-Measured Sedentary Accumulation Patterns With Incident Cardiovascular Disease, Cancer, and All-Cause Mortality. J Am Heart Assoc. 2022 May 3;11(9):e023845. doi: 10.1161/JAHA.121.023845
Biddle GJH, Henson J, Biddle SJH, Davies MJ, Khunti K, Rowlands AV, Sutton S, Yates T, Edwardson CL. Modelling the Reallocation of Time Spent Sitting into Physical Activity: Isotemporal Substitution vs. Compositional Isotemporal Substitution. Int J Environ Res Public Health. 2021 Jun 8;18(12):6210. doi: 10.3390/ijerph18126210
Hadgraft NT, Winkler E, Climie RE, Grace MS, Romero L, Owen N, Dunstan D, Healy G, Dempsey PC. Effects of sedentary behaviour interventions on biomarkers of cardiometabolic risk in adults: systematic review with meta-analyses. Br J Sports Med. 2021 Feb;55(3):144-154. doi: 10.1136/bjsports-2019-101154
Dempsey PC, Biddle SJH, Buman MP, Chastin S, Ekelund U, Friedenreich CM, Katzmarzyk PT, Leitzmann MF, Stamatakis E, van der Ploeg HP, Willumsen J, Bull F. New global guidelines on sedentary behaviour and health for adults: broadening the behavioural targets. Int J Behav Nutr Phys Act. 2020 Nov 26;17(1):151. doi: 10.1186/s12966-020-01044-0
Henson J, Edwardson CL, Celis-Morales CA, Davies MJ, Dunstan DW, Esliger DW, Gill JMR, Kazi A, Khunti K, King J, McCarthy M, Sattar N, Stensel DJ, Velayudhan L, Zaccardi F, Yates T. Predictors of the Acute Postprandial Response to Breaking Up Prolonged Sitting. Med Sci Sports Exerc. 2020 Jun;52(6):1385-1393. doi: 10.1249/MSS.0000000000002249
Yates T, Edwardson CL, Henson J, Zaccardi F, Khunti K, Davies MJ. Prospectively Reallocating Sedentary Time: Associations with Cardiometabolic Health. Med Sci Sports Exerc. 2020 Apr;52(4):844-850. doi: 10.1249/MSS.0000000000002204
Edwardson CL, Henson J, Biddle SJH, Davies MJ, Khunti K, Maylor B, Yates T. activPAL and ActiGraph Assessed Sedentary Behavior and Cardiometabolic Health Markers. Med Sci Sports Exerc. 2020 Feb;52(2):391-397. doi: 10.1249/MSS.0000000000002138
Ekelund U, Tarp J, Steene-Johannessen J, Hansen BH, Jefferis B, Fagerland MW, Whincup P, Diaz KM, Hooker SP, Chernofsky A, Larson MG, Spartano N, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma E, Anderssen SA, Lee IM. Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis. BMJ. 2019 Aug 21;366:l4570. doi: 10.1136/bmj.l4570
Edwardson CL, Yates T, Biddle SJH, Davies MJ, Dunstan DW, Esliger DW, Gray LJ, Jackson B, O’Connell S, Waheed G, Munir F. The effectiveness of the Stand More AT (SMArT) Work intervention: A cluster randomised control trial. BMJ. 2018. doi: 10.1136/bmj.k3870
Yates T, Edwardson C, Celis-Morales C, Biddle S, Davies MJ, Esliger D, Henson J, Kazi A, Khunti K, Sattar N, Sinclair AJ, Rowlands A, Velayudhan L, Zaccardi F, Gill JMR. Metabolic Effects of Breaking Prolonged Sitting With Standing or Light Walking in Older South Asians and White Europeans: A Randomized Acute Study. The journals of gerontology. Series A, Biological sciences and medical sciences. 2018 Nov 7. doi: 10.1093/gerona/gly252
McCarthy M, Edwardson CL, Davies MJ, Henson J, Rowlands A, King JA, Bodicoat DH, Khunti K, Yates T. Breaking up sedentary time with seated upper body activity can regulate metabolic health in obese high-risk adults: A randomized crossover trial. Diabetes Obes Metab. 2017 Dec;19(12):1732-1739. doi: 10.1111/dom.13016
McCarthy M, Edwardson CL, Davies MJ, Henson J, Bodicoat DH, Khunti K, Dunstan DW, King JA, Yates T. Fitness Moderates Glycemic Responses to Sitting and Light Activity Breaks. Med Sci Sports Exerc. 2017 Nov;49(11):2216-2222. doi: 10.1249/MSS.0000000000001338
Wilmot EG, Edwardson CL, Achana FA, Davies MJ, Gorely T, Gray LJ, Khunti K, Yates T, Biddle SJ. Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis. Diabetologia. 2012 Nov;55(11):2895-905. doi: 10.1007/s00125-012-2677-z